Following the completion of his undergraduate studies at Cornell University, where he graduated with distinction in all subjects, Dr Wu went on to Tulane University School of Medicine to pursue his medical education. During this time he was awarded a Pew Research Fellowship that allowed him to spend a year at the Rockefeller University in New York. He then trained at Columbia Presbyterian Hospital in New York City (internship), the Mount Sinai Medical Center in New York City (ophthalmology residency), and the National Retina Institute in Baltimore under the mentorship of Drs Bert Glaser and Robert Murphy (vitreoretinal fellowship). In 1999, Dr Wu returned to Costa Rica where he was appointed Associate Professor at the University of Costa Rica and the Director of the Asociados de Macula Vitreo y Retina de Costa Rica in San José, Costa Rica. Dr Wu is a founding member of the Pan American Collaborative Retina Study (PACORES) Group. He has authored and co-authored more than 95 peer reviewed articles, more than 46 chapters and has edited 5 books. He has been awarded the Senior Honor Award (2007) by the American Society of Retina Specialists, Senior Honor Award (2010) by the Greek Vitreoretinal Society, Achievement Award (2006) and the Senior Achievement Award (2013) by the American Academy of Ophthalmology. In 2018 he was inducted into the Retina Hall of Fame. In addition, he was the 2014 Sociedad Panamericana de Retina y Vitreo GLADAOF Lecturer and the 2017 American Journal of Ophthalmology Lecturer at the PAAO meeting. He sits on the editorial board of the American Journal of Ophthalmology, Retina Cases and Brief Reports, Journal of VitreoRetinal Diseases and the International Journal of Retina and Vitreous among others.

Dr Wu is past President of the Pan American Retina and Vitreous Society and served as the Vice-President for the Pan American Association of Ophthalmology. He is currently a member of the Club Jules Gonin Executive Committee and the Vail Vitrectomy Program Committee. He also served two terms as President of the Costa Rican Ophthalmological Association. He also served in the Board of Trustees of the AAO. In addition, he is certified by the American Board of Ophthalmology. He is a member of the Club Jules Gonin, Macula Society, Retina Society and the American Society of Retinal Specialists. Dr Wu has been invited to speak at several international meetings like the American Academy of Ophthalmology Retina Subspecialty Day and the Vail Vitrectomy Meeting.